• Annuaire
  • Localisation
  • Publications
  • Intranet
  • Réservations
  • Français Français Français fr
  • English English Anglais en
IEMN
  • Accueil
  • Actualités
    • A la Une
    • IRMMW-THz 2019 Student Workshop
    • Toutes les actualités
    • Les sujets de thèse 2019
    • Offres de stage de Master2 2018-2019
    • Les offres d’emplois
  • L’institut
    • Présentation
    • Organisation de l’institut
    • La direction scientifique
    • La direction technique
    • La direction administrative et financière
  • La Recherche
    • Les départements scientifiques
      • Matériaux et Nanostructures
      • Micro et nanosystèmes
      • Micro/nano et optoélectronique
      • Systèmes de communication et application micro-ondes
      • Acoustique
    • Les groupes de recherche
      • Groupe : ACOUSTIQUE
      • Groupe : AIMAN-FILMS
      • Groupe : ANODE
      • Groupe : BioMEMS
      • Groupe : CARBON
      • Groupe : CSAM
      • Groupe : COMNUM
      • Groupe : DOME
      • Groupe : EPIPHY
      • Groupe : MAMINA
      • Groupe : MICROELEC SI
      • Groupe : MITEC
      • Groupe : NCM
      • Groupe : NAM6
      • Groupe: NBI
      • Groupe : OPTO
      • Groupe : PHOTONIQUE THz
      • Groupe : PHYSIQUE
      • Groupe : PUISSANCE
      • Groupe : SILPHYDE
      • Groupe : TELICE
      • Groupe : TPIA
    • Publications
    • Dossier quadriennal
  • Les Plates-Formes
    • Plate-forme Centrale de Micro Nano Fabrication (CMNF)
    • Plate-forme Caractérisation Haute Fréquence
    • Plate-forme Microscopie Champ Proche
    • Plate-forme Compatibilité Electro Magnétique
    • Plate-forme Systèmes de communications avancées « SigmaCOM »
    • Prestations proposées par nos plates-formes
  • Partenariat – Valorisation
    • Les Collaborations Académiques
    • Projets européens
    • Principales collaborations internationales
    • Les partenariats industriels
    • Les laboratoires communs IEMN-Industrie
    • Les Start-up
    • LICS-LEMAC
  • La Formation
    • IRMMW-THz 2019 Student Workshop
    • La formation par et pour la recherche
      • Master Réseaux et Télécommunications
      • MRT à distance
      • Master de Physique biologique et médicale
      • Masters DOAE adossés à l’ISTV
      • Ecoles d’ingénieur
      • La Licence Professionnelle Métrologie
      • Nano-Ecole
    • Les études doctorales à l’IEMN
    • Offres de stage de Master2 2018-2019
    • Les sujets de thèse 2019
    • Différents financements de thèse
    • Soutenances
      • Soutenances 2018
      • Soutenances 2017
      • Soutenances 2016
      • Soutenances 2015
      • Soutenances 2014
      • Soutenances 2013
    • Après la Thèse de Doctorat
      • Faire un post-doc à l’IEMN
      • FOCUS sur un ingénieur SATT issu de l’IEMN
      • Vers le monde des entreprises et de l’industrie
      • Devenir Enseignant-Chercheur
      • Devenir Chercheur
      • Créer son entreprise
  • Rechercher
  • Menu

  GROUPE DE RECHERCHE : NANO BIO INTERFACES

  • Introduction
  • Members
  • Facilities
  • Projets
  • Research activity
  • Other groups

NBI Research Activity

Overview

The NanoBioInterfaces group (NBI) is working on a number of different areas of Materials, Analytical and Biomedical Chemistry. All projects involve the fabrication and characterisation of new nanostructures and very often their surface modification and/or bioconjugation with biomolecules (peptides, proteins, aptamers, etc). Most projects are inspired by a question of medical or bio-analytical relevance and we collaborate closely with partners in Biology and Medicine on a national and international level.

ELECTROCHEMICAL-TRIGGERED RELEASE OF DRUGS

The release of drugs in a controlled manner over long-term periods has been recognized as one of the most promising biomedical technologies for treatment of certain types of diseases. Medical conditions such as cancer, diabetes and chronic pain require medications that must be dosed intermittently on demand and over a long period of time. The use of an electrical signal is considered as an attractive way when drug delivery on demand is requested. The approach is simple, safe, and inexpensive and has a wide range of possibilities to trigger the release. Changing the bias of the applied potential, the current density, using continuous or pulsed conditions, negative or positive potential bias, short or long cycles all allow in a unique manner the on-demand release of drugs.

Together with advances in nanotechnology, enabling the realization of miniaturized electrical systems and circuits on almost standard bases make electrically triggered drug release very appealing. Our group is working to develop flexible electrode patches based on graphene nanostructures which can be loaded with drugs at will and electrochemically delivered without losing its biological activity

ANTIBACTERIAL AND ANTI-BIOFILM ACTIVITIES OF NANOSTRUCTURES

Growing resistance of bacteria to antibiotics is a major health concern. Novel strategies aiming to reduce the amount of antibiotics, but able to prevent and treat animal and human infections should be investigated, evidenced and approved. Among the various approaches, the use of nanostructures is currently considered as a highly promising strategy to overcome microbial drug resistance. Carbon based nanostructures (diamond particles, graphene, etc) offer great promise for such novel activity, and research in our group is focusing on the synthesis of novel functional (mainly sugar based) carbon nanostructures with intrinsic or triggerable antibacterial properties. Photothermal ablation (PTT) and photodynamic treat (PDT) are at the forefront of our investigations.

TRANSDERMAL DELIVERY OF DRUGS

The development of a skin-mounted patch capable of controlled transcutaneous delivery of therapeutics through thermal activation provides a unique solution for the controlled release of active principles over long-term periods. Our group is exploiting different graphene based skin patches and hydrogels for on-demand transdermal drug delivery using photothermal skin activation. The concept has been shown for insulin and ondansetron, but is currently widened to other drugs.

ELECTROCHEMICAL AND PLASMONIC BASED BIOSENSING

The use of biosensors for the early diagnosis of diseases has become widely accepted. These sensors are based on the detection of disease markers (e.g. proteins overexpressed in blood and serum) and provide a point-of-care diagnosis that is rapid and cheap with appropriate specificity and sensitivity. However, biomarkers are present at very low concentrations in biological liquids (serum, urine, salvia) and the use of devices with extremely high sensitivity is requested. Our team develops novel sensing interfaces based on graphene nanomaterials and composites together with aptamer-based surface ligands, for sensitive and selective sensing of biomarkers (folic acid protein, lysozyme, cardiovascular disease markers, etc) in serum samples. Electrochemical and plasmonic read outs are at the preferred transducers used.

CANCER TREATMENT WITH NANOSTRUCTURES

while surgery and chemotherapy remain the major therapeutic approaches for the treatment of a wide range of cancers, nanoparticle-based anticancer therapies have been extensively developed over the last years as an effective treatment of advanced-stage cancers. Our team investigates particle based photothermal and photodynamic therapeutic approaches as alternative treatments. Lipid nanoparticles, as well as graphene based nanostructures are at the forefront of investigation.

SURFACE ASSISTED LASER DESORPTION IONISATION (SALDI)

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), constitutes one of the soft ionization techniques and has been successfully used to analyze large molecules. Using inorganic species as the assisting material in MALDI this approach can also be applied to low-molecular weight compounds (< 500 Da). Our team exploits silicon and diamond nanowires surfaces as SALDI matrixes together with adapted surfaced chemistry strategies for the identification and quantification of biological products and biomarkers. [/av_textblock] [av_hr class='short' height='50' shadow='no-shadow' position='left' custom_border='av-border-thin' custom_width='50px' custom_border_color='' custom_margin_top='30px' custom_margin_bottom='30px' icon_select='yes' custom_icon_color='' icon='ue808' font='entypo-fontello' av_uid='av-jo4d99tz' admin_preview_bg=''] [av_textblock size='' font_color='' color='' av-medium-font-size='' av-small-font-size='' av-mini-font-size='' av_uid='av-jo4d3e5o' admin_preview_bg='']

SYPERHYDROPHOBIC INTERFACES

The rapid development of modern transportation, petrochemical and marine engineering aggravates the environmental pollution, which not only leads to ecological disturbance but also endangers the sustainable development of society.

Chemical industrial wasterwaters usually contain organic and inorganic matter in varying concentrations that exceed the primary drinking water standards, many of them being toxic, carcinogenic or simply non biodegradable. This waste water management has become of high importance over the last years worldwide. Our group develops simple and sustained appoaches to tackle this problem through the use of superhydrophobic polyurethane sponge with excellent oil/water separation behavior and high organic adsorption capacity. Also we apply advanced oxidation processes (photocatalysis, Fenton,…) for wastewater treatment usind divers nanostructures.

GRAPHENE BASED SUPERCAPACITORS

Supercapacitors (SCs) are energy storage devices with an immense potential to resolve energy related issues. Our group focuses on the development of microchip-based electrochemical energy storage systems using porous carbon coated silicon nanowires as well as dopee/functional/ porous reduced graphene oxide nanostructures as SCS candidates.

  • Les départements de recherche
    • Physique des nanostructures
    • Micro et nanosystèmes
    • Micro/nano et optoélectronique
    • Systèmes de communication et application micro-ondes
    • Acoustique
  • Les groupes de recherche
    • Groupe : ACOUSTIQUE
      • Members
      • Collaborations
      • Equipments
      • Contracts
      • On-going studies
    • Groupe : AIMAN-FILMS
      • Members
      • Results
      • Collaborations
      • Figures and facts
      • LIA LEMAC and LIA LICS
      • ANR CAMELOTT
    • Groupe : ANODE
      • Team members
      • Solid State THz Electronic Activities
      • III-V Materials for more Moore Activity
      • Nano-Device Characterization
    • Groupe : BioMEMS
    • Groupe : CARBON
      • Members
      • Research Areas
      • Gracy Project
      • FlexiGaN
      • Technologies
      • Partnerships
      • Job Opening
      • Lycéens et grand public
    • Groupe : COMNUM
      • Membres
      • Transports Intelligents
      • Systèmes de transmission vidéo numérique
      • Systèmes de Communications Multi-Utilisateurs
    • Groupe : CSAM
      • Membres
      • Systèmes radiofréquences et circuits intégrés
      • Objets Connectés
      • Micro-stockage de l’énergie
    • Groupe : DOME
      • Membres
      • Offre de Thèse
      • Offre de Post-Doctorat
    • Groupe : EPIPHY
      • Team members
        • Alexandre BUCAMP
        • Ludovic DESPLANQUE
        • Jawad HADID
        • Djamila HOURLIER
        • Shivani SHISODIA
        • Dominique VIGNAUD
        • Xavier WALLART
      • Masters – PhDs
      • Equipment
      • On-going studies
      • Publications
    • Groupe : MAMINA
    • Groupe : MICROELEC SI
      • Team members
      • Research Projects
      • Publications
      • News
      • Positions
    • Groupe : MITEC
      • Membres
      • Collaborations
      • Thématiques
    • Groupe : NAM6
      • Members
      • On going studies
      • Projects – Contracts
    • Groupe: NBI
      • Team members
      • Facilities
      • Projects
      • Research activity
    • Groupe : NCM
      • People
        • Dominique Vuillaume
      • Research activities
      • Projects
      • Publications
    • Groupe : OPTO
      • Membres
      • Projets
      • Publications
      • Offres d’emploi
    • Groupe : PHOTONIQUE THz
      • Members
        • Stefano BARBIERI
        • Fuanki BAVEDILA
        • Maximilien BILLET
        • Sara BRETIN
        • Yann DESMET
        • Guillaume DUCOURNAU
        • Kevin FROBERGER
        • Cybelle GONCALVES
        • Michael HAKL
        • Tomáš HORÁK
        • Jean-François LAMPIN
        • Quyang LIN
        • Sergey MITRYUKOVSKIY
        • Romain PERETTI
        • Emilien PEYTAVIT
        • Oleksandr STEPANENKO
        • Joan TURUT
        • Mathias VANWOLLEGHEM
      • Research
      • Publications
    • Groupe : PHYSIQUE
      • Electrostatics and Physics of Nanosructures
        • Members
        • On-going activities
      • EPHONI
        • Members
        • Funded projects
      • NAMASTE
        • Members
        • Projets
      • Nanoacoustics
        • Members
      • Physics of Nanostructures & Quantum Devices
        • Research activities
        • Members
        • Job opportunities
        • Media reports
    • Groupe : PUISSANCE
      • Members
        • Nour Eddine BOURZGUI
        • Jean-Claude DE JAEGER
        • Nicolas DEFRANCE
        • Christophe GAQUIÈRE
        • Marie LESECQ
        • Michel ROUSSEAU
      • Research
        • AlGaN/GaN HEMT thermal modeling and characterization
        • Measurement above 110GHz
        • Modelling of GaN-HEMT for high efficiency power converters
        • Nanoribbon-channel AlGaN/GaN HEMTs
        • New technological routes to improve thermal managements in GaN HEMTs
        • Power performance at 40GHz of AlGaN/GaN HEMTs on silicon substrate
        • Temperature monitoring of operating AlGaN/GaN HEMTs
    • Groupe : SILPHYDE
      • Members
      • Research
        • Simulation of nitride-based electronic devices
        • Modeling of THz sources based on Quantum Cascade Lasers
        • Study of ferroelectric nanostructures
        • Monte Carlo simulation of 2D materials for electronic and spintronic applications
    • Groupe : TELICE
      • Members
      • On going studies
      • Job opportunities
    • Groupe : TPIA
  • Dossier quadriennal

Étiquettes

autonotex BIOMEMS cancer CNRS Communications conference emploi Equipex EuraTechnologies Excelsior exposition Flagship Galerkin discontinu Graphene hyperfréquences IA IEMN IEMN - Nanotechnologie - transistors - HEMT ingénieur d’étude Intelligence artificielle iwsent Japon meeting microscopie Microscopy Microwave Nanoecole Nanora nanoscale Nanotechnologie non-stœchiométriques ondes optoélectronique Peytral radar Renatech semi-conducteurs Seminar SMILLE-E Séminaire Thèse ultrasons véhicule Wavely Wireless
Suivresur TwitterS'inscrirevers flux RSS

IEMN – Laboratoire Central de l’Institut

Cité Scientifique
Avenue Henri Poincaré
CS 60069
59 652 Villeneuve d'Ascq Cedex, France

+33 (0)3 20 19 79 79

Derniers articles

  • Offre d’emploi : OPEN PhD POSITION – Development of robotic on-wafer probing station based on piezo-driven linear and rotation positioning stages for high frequency nanoelectronics metrology10 décembre 2019 - 10 h 42 min
  • L’IEMN et l’IRCICA sont impliqués dans la création d’une rétine artificielle qui vient remplacer une rétine endommagée.26 novembre 2019 - 15 h 24 min
  • Soutenance de thèse: Abir SWAIDAN – Préparation de matériaux nanostructurés et leur application en tant qu’enzymes mimétiques pour la détection et la lutte antibactérienne4 décembre 2019 - 16 h 07 min
  • Soutenance de thèse: Anthony TRIOUX – Etude et optimisation d’un système de vidéotransmission conjoint source-canal basé « SoftCast »28 novembre 2019 - 16 h 21 min
  • Séminaire: Quantum Mechanics and Spectroscopy of Molecular Endofullerenes5 décembre 2019 - 15 h 09 min

Horaires de l’accueil du Laboratoire Central

Lundi - Jeudi: 8:30 à 12:00 | 13:30 à 16:30
Vendredi: 8:30 à 12:00 | 13:30 à 16:00
Samedi - Dimanche: Fermé

© Copyright Service ECM et pôle SISR - powered by Enfold WordPress Theme
  • Plan du site
  • Localisation
  • Visite
  • Publications
  • Intranet
  • Contact
  • Mentions légales
  • Politique de confidentialité
Faire défiler vers le haut

Certaines fonctionnalités de ce site (partage de contenus sur les réseaux sociaux, lecture directe de vidéos, ...) s’appuient sur des services proposés par des sites tiers. Ces fonctionnalités déposent des cookies permettant notamment à ces sites de tracer votre navigation. En continuant votre navigation sur ce site, vous acceptez donc, de fait, leur utilisation.

OK