{"id":71325,"date":"2024-10-31T16:37:54","date_gmt":"2024-10-31T14:37:54","guid":{"rendered":"https:\/\/www.iemn.fr\/?p=71325"},"modified":"2024-10-31T16:40:31","modified_gmt":"2024-10-31T14:40:31","slug":"micro-nanomaterials-in-biomolecular-sensing","status":"publish","type":"post","link":"https:\/\/www.iemn.fr\/en\/a-la-une\/micro-nanomaterials-in-biomolecular-sensing.html","title":{"rendered":"Lorena Manzanares seminar - Micro\/nanomaterials in biomolecular sensing: 10 December 11am in Amphi LCI"},"content":{"rendered":"<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-292fyq-b7c18688d44b1dba2b5a99f503253567\">\n.flex_column.av-292fyq-b7c18688d44b1dba2b5a99f503253567{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-292fyq-b7c18688d44b1dba2b5a99f503253567 av_one_full  avia-builder-el-0  avia-builder-el-no-sibling  first flex_column_div av-zero-column-padding'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lu9trtjd-cd429c0d25c9984d4ac3759ef1f89fee\">\n#top .av_textblock_section.av-lu9trtjd-cd429c0d25c9984d4ac3759ef1f89fee .avia_textblock{\nfont-size:20px;\ncolor:#edae44;\n}\n<\/style>\n<section  class='av_textblock_section av-lu9trtjd-cd429c0d25c9984d4ac3759ef1f89fee'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock av_inherit_color'  itemprop=\"text\" ><h1 style=\"text-align: center;\">\" M<span lang=\"EN-US\">icro\/nanomaterials in biomolecular sensing\".<\/span><\/h1>\n<h4><\/h4>\n<h4 style=\"text-align: center;\">by Lorena Manzanares, Junior Professor at Centrale Lille and IEMN.<\/h4>\n<p style=\"text-align: center;\"><strong>December, 10th (Thu) 11:00 am , at the IEMN Amphitheatre<br \/>\n<\/strong><\/p>\n<p style=\"text-align: center;\">We invite you to attend this seminar as part of the \"Technologies for Health\" and \"Materials\" flagships.<\/p>\n<hr \/>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lu9u4tln-8a5ed3853ce184a98fb030c8952623b5\">\n#top .av_textblock_section.av-lu9u4tln-8a5ed3853ce184a98fb030c8952623b5 .avia_textblock{\nfont-size:16px;\n}\n<\/style>\n<section  class='av_textblock_section av-lu9u4tln-8a5ed3853ce184a98fb030c8952623b5'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p><strong><span style=\"color: #008080;\">\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mqde7m-ed0d3d89940e7bb979d711dc9a97aa62\">\n.av_font_icon.av-mqde7m-ed0d3d89940e7bb979d711dc9a97aa62{\ncolor:#08080;\nborder-color:#08080;\n}\n.av_font_icon.av-mqde7m-ed0d3d89940e7bb979d711dc9a97aa62 .av-icon-char{\nfont-size:35px;\nline-height:35px;\n}\n<\/style>\n<span  class='av_font_icon av-mqde7m-ed0d3d89940e7bb979d711dc9a97aa62 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-icon-animate'><span class='av-icon-char' aria-hidden='true' data-av_icon='\ue885' data-av_iconfont='entypo-fontello' ><\/span><\/span> ABSTRACT<\/span><\/strong><\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lu9tvu7q-a2fc660ccaa6956e44a3fddf90c22f0e\">\n#top .av_textblock_section.av-lu9tvu7q-a2fc660ccaa6956e44a3fddf90c22f0e .avia_textblock{\nfont-size:12px;\n}\n<\/style>\n<section  class='av_textblock_section av-lu9tvu7q-a2fc660ccaa6956e44a3fddf90c22f0e'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><p style=\"margin: 0px; font-size: 16px; font-family: Calibri, sans-serif; color: #000000; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: #fcfdfe; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; text-align: justify;\"><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\"><span style=\"font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: #0C00; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\">his seminar explores <\/span><span style=\"font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\">several ways in which <\/span><span style=\"font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: #0C00; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\">micro- and nanomaterials <\/span><span style=\"font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\">can be used <\/span><span style=\"font-size: 11.0pt; font-family: 'Aptos',sans-serif; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: #0C00; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;\">in biosensing, focusing on their roles in electrochemical and optical systems. <\/span><\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">On the electrochemical side, I will discuss my experience using biofunctionalized superparamagnetic microparticles in DNA sensors and the benefits of that approach for real-sample analysis. Next, I will present our work on 3D-printed graphene\/polymer electrodes, where we transformed printed (plastic) objects into highly sensitive electroanalytical platforms, demonstrating several proof-of-principle sensing applications.<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">Moving beyond electrochemistry, I will introduce how 2D materials, such as graphene and its derivatives, are employed in fluorescence sensing, using DNA detection as a prime example. I will then highlight our research on MXenes (known as \" hydrophilic metals \", composed of 2D early transition metal carbides, nitrides and\/or carbonitrides), focusing on their unique interactions with DNA and understanding their distance-dependent quenching behavior using single-molecule techniques and DNA nanostructures.<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">Building on these findings, we\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">currently\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">exploit MXene-based nonradiative energy transfer to achieve precise nanoscale measurements with fluorescence microscopy. This approach not only allows us to study nanoscale biological phenomena, such as leaflet-resolved sensing in lipid bilayers (biomembrane models) at the single molecule level,<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0but it can also be used for\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">characterizing 2D materials with high resolution (nanocharacterization).<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">The seminar concludes with ongoing efforts at IEMN within the Chaire de Professeur Junior (CPJ) scheme, where we aim to integrate these biosensing advancements<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">, particularly 2D materials and DNA nanotech,<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0with AIMAN FILMS's\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">acoustic\u00a0<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">technolog<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">ies<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">\u00a0to develop diagnostic devices for breast cancer<\/span><span style=\"font-size: 11pt; font-family: aptos, sans-serif; color: black;\">.<\/span><\/p>\n<\/div><\/section><\/p><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":20,"featured_media":69379,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,8,87,65,84],"tags":[],"class_list":["post-71325","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-a-la-une","category-actualites","category-agenda-en","category-agenda","category-agenda-en-en"],"_links":{"self":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/71325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/comments?post=71325"}],"version-history":[{"count":0,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/71325\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media\/69379"}],"wp:attachment":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media?parent=71325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/categories?post=71325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/tags?post=71325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}