{"id":62652,"date":"2024-02-27T11:04:35","date_gmt":"2024-02-27T09:04:35","guid":{"rendered":"https:\/\/www.iemn.fr\/?p=62652"},"modified":"2024-02-27T11:09:20","modified_gmt":"2024-02-27T09:09:20","slug":"these-elias-v-an-approach-based-on-the-%c2%b5-vibration-concept-contributes-to-the-characterization-and-objective-analysis-of-physiological-fluids","status":"publish","type":"post","link":"https:\/\/www.iemn.fr\/en\/these-2023\/these-elias-v-an-approach-based-on-the-%c2%b5-vibration-concept-contributes-to-the-characterization-and-objective-analysis-of-physiological-fluids.html","title":{"rendered":"THESIS: ELIAS Victory - An approach based on the \u00b5-vibration concept contributes to the characterization and objective analysis of physiological fluids"},"content":{"rendered":"<div id='layer_slider_1'  class='avia-layerslider main_color avia-shadow  avia-builder-el-0  el_before_av_heading  avia-builder-el-first  container_wrap sidebar_right'  style='height: 261px;'  ><div id=\"layerslider_58_1mxvs1sdog0la\" data-ls-slug=\"homepageslider\" class=\"ls-wp-container fitvidsignore ls-selectable\" style=\"width:1140px;height:260px;margin:0 auto;margin-bottom: 0px;\"><div class=\"ls-slide\" data-ls=\"duration:6000;transition2d:5;\"><img loading=\"lazy\" decoding=\"async\" width=\"2600\" height=\"270\" src=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1.jpg\" class=\"ls-bg\" alt=\"\" srcset=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1.jpg 2600w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1-300x31.jpg 300w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1-768x80.jpg 768w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1-1030x107.jpg 1030w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1-1500x156.jpg 1500w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2019\/01\/sliders_news1-705x73.jpg 705w\" sizes=\"auto, (max-width: 2600px) 100vw, 2600px\" \/><ls-layer style=\"font-size:14px;text-align:left;font-style:normal;text-decoration:none;text-transform:none;font-weight:700;letter-spacing:0px;border-style:solid;border-color:#000;background-position:0% 0%;background-repeat:no-repeat;width:180px;height:30px;left:0px;top:231px;line-height:32px;color:#ffffff;border-radius:6px 6px 6px 6px;padding-left:50px;background-color:rgba(0, 0, 0, 0.57);\" class=\"ls-l ls-ib-icon ls-text-layer\" data-ls=\"minfontsize:0;minmobilefontsize:0;\"><i class=\"fa fa-quote-right\" style=\"color:#ffffff;margin-right:0.8em;font-size:1em;transform:translateY( -0.125em );\"><\/i>ACTUALITES<\/ls-layer><\/div><\/div><\/div><div id='after_layer_slider_1'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-62652'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-av_heading-bca9a874bb4c43e0e68e9522c2696e85\">\n#top .av-special-heading.av-av_heading-bca9a874bb4c43e0e68e9522c2696e85{\nmargin:0 0 10px 0;\npadding-bottom:4px;\n}\nbody .av-special-heading.av-av_heading-bca9a874bb4c43e0e68e9522c2696e85 .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n.av-special-heading.av-av_heading-bca9a874bb4c43e0e68e9522c2696e85 .av-subheading{\nfont-size:15px;\n}\n<\/style>\n<div  class='av-special-heading av-av_heading-bca9a874bb4c43e0e68e9522c2696e85 av-special-heading-h2  avia-builder-el-1  el_after_av_layerslider  el_before_av_hr  avia-builder-el-first'><h2 class='av-special-heading-tag'  itemprop=\"headline\"  >THESE : ELIAS V. &#8211; An approach based on the \u00b5-vibration concept contributes to the characterization and objective analysis of physiological fluids <\/h2><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-18u73nj-dad6a947580930e400fc42ba200e80f1\">\n#top .hr.av-18u73nj-dad6a947580930e400fc42ba200e80f1{\nmargin-top:5px;\nmargin-bottom:5px;\n}\n.hr.av-18u73nj-dad6a947580930e400fc42ba200e80f1 .hr-inner{\nwidth:100%;\n}\n<\/style>\n<div  class='hr av-18u73nj-dad6a947580930e400fc42ba200e80f1 hr-custom  avia-builder-el-2  el_after_av_heading  el_before_av_textblock  hr-left hr-icon-no'><span class='hr-inner inner-border-av-border-thin'><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<section  class='av_textblock_section av-jriy64i8-2f4600354c0449b610997916bbd9b6bc'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" >\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-13ewzjw-68e036126b913e5028f77311dc66b825\">\n.av_font_icon.av-13ewzjw-68e036126b913e5028f77311dc66b825{\ncolor:#bfbfbf;\nborder-color:#bfbfbf;\n}\n.av_font_icon.av-13ewzjw-68e036126b913e5028f77311dc66b825 .av-icon-char{\nfont-size:60px;\nline-height:60px;\n}\n<\/style>\n<span  class='av_font_icon av-13ewzjw-68e036126b913e5028f77311dc66b825 avia_animate_when_visible av-icon-style- avia-icon-pos-left avia-icon-animate'><span class='av-icon-char' aria-hidden='true' data-av_icon='\ue8c9' data-av_iconfont='entypo-fontello' ><\/span><\/span>\n<p><strong>ELIAS Victory<br \/>\n<\/strong><\/p>\n<p>Soutenance : 20 D\u00e9cembre 2023<strong><br \/>\n<\/strong>Universit\u00e9 Polytechnique<\/p>\n<p>Th\u00e8se de doctorat en Micro-nano syst\u00e8mes et capteurs<\/p>\n<\/div><\/section>\n<section  class='av_textblock_section av-jtefqx33-628129dba2299b2ecd65ebfc92eac29d'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><div  class='hr av-kjh3zw-4dff888f744b728a1aca9b3a0971493a hr-default  avia-builder-el-6  avia-builder-el-no-sibling'><span class='hr-inner'><span class=\"hr-inner-style\"><\/span><\/span><\/div>\n<h5>Summary:<\/h5>\n<p>Depuis leur apparition, les MEMS ont jou\u00e9 un r\u00f4le pr\u00e9pond\u00e9rant dans l&rsquo;avancement des dispositifs \u00e9lectrom\u00e9caniques. Parmi ces concepts technologiques, Les \u00b5-poutres prennent une place consid\u00e9rable dans des applications couvrant divers domaines. Elles sont consid\u00e9r\u00e9es, selon le contexte, comme des capteurs cl\u00e9s vu leurs sensibilit\u00e9s en effet de charges, raison qui justifie nos crit\u00e8res de choix. L\u2019int\u00e9gration des \u00b5-poutres vibratoires dans un \u00b5-syst\u00e8me global d\u2019acquisitions et d\u2019analyses visant un concept &lsquo;lab-on-a-chip&rsquo; a fait l\u2019objectif principal de ce travail. Il s&rsquo;appuie principalement sur une collaboration initi\u00e9e en 2012 avec le d\u00e9partement de l\u2019oncologie de l\u2019universit\u00e9 de Goteb\u00f6rg (Su\u00e8de). Le but est d\u2019aboutir \u00e0 une technique compl\u00e9mentaire et \u2018Soft\u2019 de d\u00e9pistage pr\u00e9coce d\u2019un \u00e9tat potentiellement canc\u00e9reux touchant le sein comme organe principal. Sur la base de cette approche nous avons concentr\u00e9 nos efforts sur l&rsquo;affinement d\u2019un concept microm\u00e9trique bas\u00e9 sur l\u2019analyse des variations des caract\u00e9ristiques dynamiques et vibratoires des \u00b5-poutres consid\u00e9r\u00e9es comme des capteurs par effet de charges. En premier temps, l\u2019\u00e9tude analytique consolid\u00e9e et valid\u00e9e par une approche num\u00e9rique nous a permis de valider ensuite nos choix conceptuels exp\u00e9rimentaux. Cela, nous a conduit \u00e0 une technique de mise en r\u00e9sonance des poutres par l&rsquo;int\u00e9gration d\u2019une source \u00e9lectrom\u00e9canique (PZT) dans la structure globale assurant un couplage optimal conduisant ainsi \u00e0 une continuit\u00e9 dans le d\u00e9placement dynamique et une amplification vibratoire ma\u00eetris\u00e9e. Sur le plan technologique, les micro-poutres d\u2019une dimension de 800 \u03bcm x 140 \u03bcm x 40 \u03bcm ont \u00e9t\u00e9 r\u00e9alis\u00e9es par une gravure laser (femto) tout en tenant compte des caract\u00e9ristiques physico-chimiques et dimensionnelles optimales qui ont rendu possible l&rsquo;\u00e9valuation des grandeurs recherch\u00e9es \u00e0 la fois sur la dynamique vibratoire des capteurs ainsi que leurs comportements dans le fluide d\u2019analyse. Cette approche nous a permis d&rsquo;\u00e9tablir une relation de d\u00e9pendance entre les r\u00e9ponses vibratoires des \u00b5-poutres, d\u2019un c\u00f4t\u00e9 \u00e9valuer la nature intrins\u00e8que du fluide sous investigation et d\u2019un autre c\u00f4t\u00e9 quantifier l\u2019effet de charge d\u2019une masse ajout\u00e9e sur la surface.<\/p>\n<h5>Abstract:<\/h5>\n<p>Since their first appearance, MEMS have played a major role in the development of electromechanical devices. Among these technological concepts, \u00b5-beams play a considerable role in applications covering various fields. Depending on the context, they are considered to be key sensors because of their sensitivity to load effects, which justifies our selection criteria. The integration of vibratory \u00b5-beams into a global \u00b5-acquisition and analysis system based on a &lsquo;lab-on-a-chip&rsquo; concept was the main objective of this work. It is based primarily on a collaboration initiated in 2012 with the Department of Oncology at the University of Goteb\u00f6rg (Sweden). The aim is to develop a complementary and &lsquo;soft&rsquo; technique for the early detection of a potentially cancerous condition affecting the breast as the main organ. Based on this approach, we have concentrated our efforts on refining a micrometric concept based on the analysis of variations in the dynamic and vibratory characteristics of \u00b5-beams considered as load effect sensors. Firstly, the analytical study, consolidated and validated by a numerical approach, enabled us to validate our experimental conceptual choices. This led us to a technique for setting the beams in resonance by integrating an electromechanical source (PZT) into the overall structure to ensure optimum coupling, leading to continuity in the dynamic displacement and controlled vibration amplification. Technologically, the micro-beams, measuring 800 \u03bcm x 140 \u03bcm x 40 \u03bcm, were produced by laser engraving (femto), taking into account the optimum physico-chemical and dimensional characteristics that made it possible to assess the quantities sought both in terms of the vibratory dynamics of the sensors and their behaviour in the analysis fluid. This approach enabled us to establish a dependency relationship between the vibratory responses of the \u00b5-beams, on the one hand to assess the intrinsic nature of the fluid under investigation and on the other hand to quantify the loading effect of an added mass on the surface.<\/p>\n<\/div><\/section>","protected":false},"excerpt":{"rendered":"","protected":false},"author":20,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[318],"tags":[],"class_list":["post-62652","post","type-post","status-publish","format-standard","hentry","category-these-2023"],"_links":{"self":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/62652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/comments?post=62652"}],"version-history":[{"count":0,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/62652\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media?parent=62652"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/categories?post=62652"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/tags?post=62652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}