{"id":49009,"date":"2021-12-14T11:00:39","date_gmt":"2021-12-14T09:00:39","guid":{"rendered":"https:\/\/www.iemn.fr\/articles-temporaires-anglais\/un-controle-de-temperature-au-plus-pres-des-interactions-biologiques-pour-les-biocapteurs-2.html"},"modified":"2021-12-16T17:09:49","modified_gmt":"2021-12-16T15:09:49","slug":"un-controle-de-temperature-au-plus-pres-des-interactions-biologiques-pour-les-biocapteurs-2","status":"publish","type":"post","link":"https:\/\/www.iemn.fr\/en\/newsletter\/un-controle-de-temperature-au-plus-pres-des-interactions-biologiques-pour-les-biocapteurs-2.html","title":{"rendered":"Temperature control close to biological interactions for biosensors"},"content":{"rendered":"<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc\">\n.flex_column.av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc av_one_full  avia-builder-el-0  avia-builder-el-no-sibling  first flex_column_div av-zero-column-padding'     ><section  class='av_textblock_section av-kx5vjxze-defd5f3e3474f0b79e38d6eb21ee0825'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><h3 style=\"text-align: center;\">Temperature control close to biological interactions<br \/>\nfor biosensors<\/h3>\n<blockquote>\n<p>Biodetection based on the <strong>principle of surface plasmon resonance<\/strong> is one of the most accurate ways <strong>to detect the presence of pathogens in a fluid<\/strong>.<br \/>\nNevertheless, <strong>the temperature of the analyte under test<\/strong> must be <strong>very finely controlled<\/strong> in order not to disturb the measurements. The <strong>use of the sensor surface as a thermo-regulating element<\/strong> allows this control while simplifying its implementation, a decisive step towards the <strong>portability of detection systems<\/strong> &#8230;<\/p>\n<\/blockquote>\n<p><a href=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-49027 alignright\" src=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-300x254.png\" alt=\"\" width=\"273\" height=\"231\" srcset=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-300x254.png 300w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-14x12.png 14w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1.png 600w\" sizes=\"auto, (max-width: 273px) 100vw, 273px\" \/><\/a>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-nfupht-b714eb184f90f7ba6849490368b5fc47\">\n.av_font_icon.av-nfupht-b714eb184f90f7ba6849490368b5fc47 .av-icon-char{\nfont-size:30px;\nline-height:30px;\n}\n<\/style>\n<span  class='av_font_icon av-nfupht-b714eb184f90f7ba6849490368b5fc47 avia_animate_when_visible av-icon-style- avia-icon-pos-left av-no-color avia-icon-animate'><span class='av-icon-char' aria-hidden='true' data-av_icon='\ue832' data-av_iconfont='entypo-fontello' ><\/span><\/span><\/p>\n<p>Biodetection based on the principle of surface plasmon resonance (SPR) is a very sensitive biodetection technique currently reserved for analytical laboratories. It is a technique without labeling of the target cells (\u00ab\u00a0label free\u00a0\u00bb) contained in the analyte and whose detection specificity is linked to that of the probe cells grafted on the sensor. Its measurement principle involves only physical laws, in this case the technique measures very precisely the optical index of any material or fluid that is in the very close vicinity (a few hundred nanometers) of the sensor surface. This last one is realized by a metallic film of nanometric thickness (a few tens of nanometers).<\/p>\n<p>Whether it is the molecular interaction involved or the optical index of the solution under test, both are extremely dependent on the temperature at which the measurement is made. For this reason, a temperature control is necessary and it complicates the implementation of the system, depriving it of the portability of the measuring equipment.<\/p>\n<p>Within the framework of <strong>the cross-border INTERREG V France-Walloon Flanders project<\/strong> <a href=\"https:\/\/www.interreg-fwvl.eu\/fr\/biosens\">BIOSENS<\/a> aiming at <strong>developing a portable equipment for the detection of phyto-pathogens in the field<\/strong>, the thin metallic layer of the SPR sensor has been used as a thermo-regulating element. The injection of a current in this metallic film allows to regulate very finely the temperature and this as close as possible to the biomolecular interaction.<\/p>\n<p><a name=\"_GoBack\"><\/a> <span lang=\"en-US\">\u00ab\u00a0Plasmonic layer as localized temperature control element for surface plasmonic resonance based sensors\u00a0\u00bb, S. Ganesan, S. Maricot, J-F. Robillard, E. Okada, M-T. Bakouche, L. Hay, J-P. Vilcot, <\/span><span lang=\"en-US\"><i><b>Sensors<\/b><\/i><\/span><span lang=\"en-US\">, 21(6), <\/span><span style=\"color: #0563c1;\"><u><a href=\"https:\/\/doi.org\/10.3390\/s21062035\"><span lang=\"en-US\">2035, https:\/\/doi.org\/10.3390\/s21062035 <\/span><\/a><\/u><\/span><\/p>\n<p><strong><span lang=\"en-US\">Contact:<\/span><\/strong><\/p>\n<div  class='avia-button-wrap av-rpqvoq-f028209bb307f465dda7da7a2e25c59f-wrap avia-button-left  avia-builder-el-3  el_after_av_font_icon  avia-builder-el-last'><a href='mailto:jean-pierre.vilcot@univ-lille.fr'  class='avia-button av-rpqvoq-f028209bb307f465dda7da7a2e25c59f av-link-btn avia-icon_select-yes-left-icon avia-size-small avia-position-left avia-color-silver'   aria-label=\"jean-pierre.vilcot@univ-lille.fr\"><span class='avia_button_icon avia_button_icon_left' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/span><span class='avia_iconbox_title' >jean-pierre.vilcot@univ-lille.fr<\/span><\/a><\/div>\n<\/div><\/section><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[297],"tags":[],"class_list":["post-49009","post","type-post","status-publish","format-standard","hentry","category-newsletter"],"_links":{"self":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/49009","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/comments?post=49009"}],"version-history":[{"count":0,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/49009\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media?parent=49009"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/categories?post=49009"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/tags?post=49009"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}