{"id":49002,"date":"2021-12-14T11:00:39","date_gmt":"2021-12-14T09:00:39","guid":{"rendered":"https:\/\/www.iemn.fr\/?p=49002"},"modified":"2021-12-16T17:08:04","modified_gmt":"2021-12-16T15:08:04","slug":"un-controle-de-temperature-au-plus-pres-des-interactions-biologiques-pour-les-biocapteurs","status":"publish","type":"post","link":"https:\/\/www.iemn.fr\/en\/newsletter\/un-controle-de-temperature-au-plus-pres-des-interactions-biologiques-pour-les-biocapteurs.html","title":{"rendered":"Un contr\u00f4le de temp\u00e9rature au plus pr\u00e8s des interactions biologiques pour les biocapteurs"},"content":{"rendered":"<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc\">\n.flex_column.av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-kspn0q-0dfcff60d18dd9fb43f8237599903ccc av_one_full  avia-builder-el-0  avia-builder-el-no-sibling  first flex_column_div av-zero-column-padding'     ><section  class='av_textblock_section av-kx5vjxze-defd5f3e3474f0b79e38d6eb21ee0825'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><h3 style=\"text-align: center;\">Temperature control<\/h3>\n<h3 style=\"text-align: center;\">as close as possible to biological interactions for biosensors<\/h3>\n<h3 style=\"text-align: center;\"><\/h3>\n<blockquote>\n<p>Biodetection based on the principle of surface plasmon resonance is one of the most accurate ways of detecting the presence of pathogens in a fluid.<br \/>\nNonetheless, <strong>the temperature of the analyte under test<\/strong> must be <strong>very finely controlled<\/strong> so as not to interfere with the measurements. L'<strong>use of the collector surface as a thermoregulating element<\/strong> enables this control while simplifying its implementation, a decisive step towards the portability of detection systems ...<\/p>\n<\/blockquote>\n<p><a href=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-49027 alignright\" src=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-300x254.png\" alt=\"\" width=\"195\" height=\"165\" srcset=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-300x254.png 300w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1-14x12.png 14w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2021\/12\/Image1.png 600w\" sizes=\"auto, (max-width: 195px) 100vw, 195px\" \/><\/a><\/p>\n<p style=\"text-align: right;\">\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-this96-ce4733e123a570777ef1ef0650e0a770\">\n.av_font_icon.av-this96-ce4733e123a570777ef1ef0650e0a770 .av-icon-char{\nfont-size:30px;\nline-height:30px;\n}\n<\/style>\n<span  class='av_font_icon av-this96-ce4733e123a570777ef1ef0650e0a770 avia_animate_when_visible av-icon-style- avia-icon-pos-left av-no-color avia-icon-animate'><span class='av-icon-char' aria-hidden='true' data-av_icon='\ue832' data-av_iconfont='entypo-fontello' ><\/span><\/span><\/p>\n<p style=\"text-align: left;\">Biodetection based on the principle of surface plasmon resonance (SPR) is a highly sensitive biodetection technique currently reserved for analysis laboratories. It is a technique that does not label the target cells ('label free') contained in the analyte and whose detection specificity is linked to that of the probe cells grafted onto the sensor. The measurement principle is based solely on physical laws, in this case the technique precisely measures the optical index of any material or fluid in the very close vicinity (a few hundred nanometres) of the sensor surface. The sensor surface is made of a metal film with a nanometric thickness (a few tens of nanometres).<br \/>\nBoth the molecular interaction involved and the optical index of the solution under test are extremely dependent on the temperature at which the measurement is taken. Temperature control is therefore necessary, and this complicates the system's implementation, currently depriving it of the portability of the measurement equipment.<br \/>\nAs part of the <strong>INTERREG V France-Wallonie Flandres cross-border project<\/strong> <a href=\"https:\/\/www.interreg-fwvl.eu\/fr\/biosens\">BIOSENS<\/a>\u00a0aimed at developing portable equipment for the field detection of plant pathogens, the thin metal layer making up the SPR sensor was used as a thermoregulating element. Injecting a current into this metal film enables the temperature to be regulated very finely, as close as possible to the biomolecular interaction.<\/p>\n<p>\"Plasmonic layer as localized temperature control element for surface plasmonic resonance based sensors\", S. Ganesan, S. Maricot, J-F. Robillard, E. Okada, M-T. Bakouche, L. Hay, J-P. Vilcot, Sensors, 21(6), 2035, https:\/\/doi.org\/10.3390\/s21062035<\/p>\n<p><strong>Contact:<\/strong><\/p>\n<div  class='avia-button-wrap av-rpqvoq-f028209bb307f465dda7da7a2e25c59f-wrap avia-button-left  avia-builder-el-3  el_after_av_font_icon  avia-builder-el-last'><a href='mailto:jean-pierre.vilcot@univ-lille.fr'  class='avia-button av-rpqvoq-f028209bb307f465dda7da7a2e25c59f av-link-btn avia-icon_select-yes-left-icon avia-size-small avia-position-left avia-color-silver'   aria-label=\"jean-pierre.vilcot@univ-lille.fr\"><span class='avia_button_icon avia_button_icon_left' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/span><span class='avia_iconbox_title' >jean-pierre.vilcot@univ-lille.fr<\/span><\/a><\/div>\n<\/div><\/section><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[297],"tags":[],"class_list":["post-49002","post","type-post","status-publish","format-standard","hentry","category-newsletter"],"_links":{"self":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/49002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/comments?post=49002"}],"version-history":[{"count":0,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/49002\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media?parent=49002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/categories?post=49002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/tags?post=49002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}