{"id":41887,"date":"2020-07-01T11:30:52","date_gmt":"2020-07-01T09:30:52","guid":{"rendered":"https:\/\/www.iemn.fr\/?p=41887"},"modified":"2020-07-08T09:09:34","modified_gmt":"2020-07-08T07:09:34","slug":"des-tourbillons-sonores-pour-manipuler-des-objets-a-lechelle-microscopique","status":"publish","type":"post","link":"https:\/\/www.iemn.fr\/en\/newsletter\/des-tourbillons-sonores-pour-manipuler-des-objets-a-lechelle-microscopique.html","title":{"rendered":"Des tourbillons sonores pour manipuler des objets \u00e0 l\u2019\u00e9chelle microscopique"},"content":{"rendered":"<div id='layer_slider_1'  class='avia-layerslider main_color avia-shadow  avia-builder-el-0  el_before_av_one_full  avia-builder-el-first  container_wrap sidebar_right'  style='height: 261px;'  ><div id=\"layerslider_40_sqa5ppwrjlqc\" data-ls-slug=\"homepageslider\" class=\"ls-wp-container fitvidsignore ls-selectable\" style=\"width:1140px;height:260px;margin:0 auto;margin-bottom: 0px;\"><div class=\"ls-slide\" data-ls=\"bgposition:50% 50%;duration:6000;transition2d:5;\"><img loading=\"lazy\" decoding=\"async\" width=\"2600\" height=\"270\" src=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1.jpg\" class=\"ls-bg\" alt=\"\" srcset=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1.jpg 2600w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1-300x31.jpg 300w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1-768x80.jpg 768w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1-1030x107.jpg 1030w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1-1500x156.jpg 1500w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2018\/09\/sliders_carc1-705x73.jpg 705w\" sizes=\"auto, (max-width: 2600px) 100vw, 2600px\" \/><ls-layer style=\"font-size:14px;text-align:left;font-style:normal;text-decoration:none;text-transform:none;font-weight:700;letter-spacing:0px;background-position:0% 0%;background-repeat:no-repeat;mix-blend-mode:normal;top:231px;left:0px;height:30px;width:360px;line-height:32px;color:#ffffff;border-radius:6px 6px 6px 6px;padding-left:50px;background-color:rgba(0, 0, 0, 0.57);\" class=\"ls-l ls-ib-icon ls-text-layer\" data-ls=\"minfontsize:0;minmobilefontsize:0;\"><i class=\"fa fa-user-circle\" style=\"color:#f2f2f2;margin-right:0.8em;font-size:1em;transform:translateY( -0.125em );\"><\/i>RESEARCH GROUP: AIMAN-FILMS<\/ls-layer><\/div><\/div><\/div><div id='after_layer_slider_1'  class='main_color av_default_container_wrap container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-41887'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-jho8qn-c87d1126fe6062829239906a945c3358\">\n.flex_column.av-jho8qn-c87d1126fe6062829239906a945c3358{\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div  class='flex_column av-jho8qn-c87d1126fe6062829239906a945c3358 av_one_full  avia-builder-el-1  el_after_av_layerslider  avia-builder-el-no-sibling  first flex_column_div av-zero-column-padding'     ><section  class='av_textblock_section av-kc35tmwb-721d8fe13971b47b3574ae8a140a9809'   itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock'  itemprop=\"text\" ><h4 style=\"text-align: center;\">Des tourbillons sonores pour manipuler des objets \u00e0 l\u2019\u00e9chelle microscopique<\/h4>\n<p><a href=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-41888 size-full\" src=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons.jpg\" alt=\"\" width=\"964\" height=\"320\" srcset=\"https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons.jpg 964w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons-300x100.jpg 300w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons-768x255.jpg 768w, https:\/\/www.iemn.fr\/wp-content\/uploads\/2020\/07\/visuel_tourbillons-705x234.jpg 705w\" sizes=\"auto, (max-width: 964px) 100vw, 964px\" \/><\/a><\/p>\n<h5>Level 1 :<\/h5>\n<p>Manipulating micro-robots in the human body, structuring different cell strains in 3D, and immobilising and imaging micro-organisms in 3D are just a few examples of the vast range of applications opened up by acoustic tweezers. Researchers at the IEMN and INSP have demonstrated that it is possible to manipulate micro-objects without physical contact by trapping them at the heart of special wave structures called acoustic vortices. These vortices are generated by miniature chips combining the principles of holograms and active materials.<\/p>\n<h5>Level 2:<\/h5>\n<p>The capabilities offered by optical tweezers have opened up new fields of investigation in physics, crowned by the two Nobel Prizes of S. Chu and A. Ashkin. Acoustic tweezers could spark a similar revolution in the fields of biology and health, as they are non-invasive, biocompatible and can operate in opaque environments, making it possible to manipulate microscopic objects in vivo.<\/p>\n<p>Acoustic clamps, like their optical analogues, are based on an average force produced by a wave, called radiation pressure. The first evidence of the existence of this force dates back to Kepler's observations of the orientation of comet tails in the direction of propagation of sunlight. In both cases (optical and acoustic), radiation pressure is proportional to the intensity of the wave irradiating a particle divided by the speed of the wave in question. As the speed of sound (around 1500 ms-1 in a liquid) is several orders of magnitude lower than that of light (around 3\u00d7108 ms-1), this gives acoustic tweezers a clear advantage: it is possible to exert considerably higher forces with the same injected power, or conversely to use beams of very low intensity to apply the same force. This considerably reduces the risk of damage when handling biological objects.<\/p>\n<p>But one difficulty has long held back the development of acoustic tweezers: manipulating an object precisely and selectively requires localising the energy of the wave in a small portion of space. This can be achieved using focused wave beams, like those used in optical tweezers. But in acoustics, most objects of interest (solid particles, cells, etc.) are not attracted but expelled from the centre of these focused waves. Another constraint is successfully trapping a 3D object with a beam from a single direction. In fact, like the tail of a comet, the particles tend to be pushed in the direction of propagation of the wave, which makes it difficult to trap them axially. These two paradoxes have been resolved by using special wave structures called acoustic vortices.<\/p>\n<p>However, there remained a major obstacle to manipulating microscopic objects: succeeding in producing these ultrasonic vortices on microscopic scales with a system that is sufficiently miniature and transparent to be integrated into a standard microscope. This is the challenge that was recently taken up by teams from the IEMN and the INSP. They combined the principles of holographic field synthesis, active materials and manufacturing methods inherited from the semiconductor industry to produce a miniature chip capable of producing acoustic vortices and thus manipulating microscopic particles.<\/p>\n<h5>Bibliography :<\/h5>\n<p><em>[1] M. Baudoin, J.-L. Thomas, Acoustic Tweezers for particles and fluid micromanipulation, Annual Review of Fluid Mechanics, 52: 205-234 (2020)<\/em><\/p>\n<p><em>[2] M. Baudoin, J.-C. Gerbedoen, A. Riaud, O. Bou Matar, N. Smagin, J.-L. Thomas, Folding a focalized acoustical vortex on a flat holographic transducer: miniaturized selective acoustical tweezer, Science Advances 5: eaav1967 (2019)<\/em><\/p>\n<div  class='avia-button-wrap av-rpqvoq-fae4d0ef02b2fd8540b9d886e8f108e7-wrap avia-button-left  avia-builder-el-3  avia-builder-el-no-sibling'><a href='mailto:michael.baudoin@univ-lille.fr'  class='avia-button av-rpqvoq-fae4d0ef02b2fd8540b9d886e8f108e7 av-link-btn avia-icon_select-yes-left-icon avia-size-small avia-position-left avia-color-silver'   aria-label=\"Contact: Micha\u00ebl BAUDOIN\"><span class='avia_button_icon avia_button_icon_left' aria-hidden='true' data-av_icon='\ue805' data-av_iconfont='entypo-fontello'><\/span><span class='avia_iconbox_title' >Contact: Micha\u00ebl BAUDOIN<\/span><\/a><\/div>\n<\/div><\/section><\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[297],"tags":[],"class_list":["post-41887","post","type-post","status-publish","format-standard","hentry","category-newsletter"],"_links":{"self":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/41887","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/comments?post=41887"}],"version-history":[{"count":0,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/posts\/41887\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/media?parent=41887"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/categories?post=41887"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.iemn.fr\/en\/wp-json\/wp\/v2\/tags?post=41887"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}