The creation of new compagnies is an interesting alternative to the tra,sfert of research results to regional SMEs. On the back of a host of information campaigns, there has been a recent increase in business start-up activity in our sphere of expertise. The “IEMN-Transfert” manager is the local point of access for young researchers to encourage meetings within the Institute between researchers and business start-up specialists. “IEMN-Transfert is involved in terms of providing advice, arranging meetings with institutional, financial or legal partners in close co-operation with the regional business support structures, participating in trade shows or business conventions and offering administrative help for preparing and monitoring contract quotations. We can mention several recent spin offs : MC2, DELFMEMS.