Séminaire MNMB : Analyse biomécanique et fluidique des anévrismes aortiques – Francesca Condemi

Francesca Condemi, chercheuse post-doctorante à l’École Nationale Supérieure des Mines de Saint-Étienne, viendra nous présenter ses travaux sur l’analyse biomécanique et fluidique des anévrismes aortiques.

Date : Vendredi 5 mai 2017 – 13h30
Lieu : Amphithéâtre – IEMN-LCI

Francesca Condemi: École Nationale Supérieure des Mines de Saint-Étienne

Abstract:

Ascending thoracic aorta aneurysm (ATAA) is known to be the 19th common cause of human death. Although prophylactic surgery is the only treatment suitable, the risk of mortality associated to elective surgical repair is up to 5%. In clinical practice, maximum diameter is the standardly used risk of rupture indicator with a critical diameter threshold of 5.5 cm. However, for aneurysms with a diameter smaller than 5.5 cm, negative outcomes (rupture, dissection and death) before surgical repair are of 5-10%.

Biomechanical studies showed that ATAA results in disturbed aortic hemodynamics and mechanical weakening of the aortic wall. However, there is still a lack of insight on how the disturbed hemodynamics and the mechanical weakening may be related.

In this talk the speaker will give a brief introduction on the methodology developed at the EMSE to analyze the fluid- and biomechanical behaviors of the ascending thoracic aorta aneurysm with concomitant aortic insufficiency (AI). This methodology combines 4D flow MRI, CFD models and the mechanical bulge inflation test to determine possible correlation between the aortic flow pattern/WSS distribution and the ATAAs wall strength in patients affected by ATAA and AI.

Biography:

Dr. Francesca Condemi obtained her PhD in Biomedical and Computer Science Engineering from the University Magna Graecia of Catanzaro (UMG), Italy in 2015. During her PhD, she was a visiting scholar at University of Kentucky (UKY), Lexington, Kentucky, USA from 2013 to 2015. She remained at UKY until March 2016 as a Postdoctoral Fellow. Currently she is a Postdoctoral Fellow at École Nationale Supérieure des Mines of Saint-Étienne (EMSE), France, in the Computational Fluid Dynamics (CFD) Branch. Her research interests revolve around the development of numerical models for the design of cardiovascular assist devices and for the analysis of the human cardiovascular system. Currently she is working on the development of a comprehensive and original model for the biomechanical analysis of the ascending thoracic aorta affected by aneurysm and concomitant aortic insufficiency (AI).